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Advanced Molecular Assays Identifies Source of Infection


A recent publication in Eurosurveillance identified the location at which EU visitors from northern European nations were infected during holiday travel. From 2000 to 2016, incident cases of Salmonella Chester were diagnosed in Norway from citizens traveling to southern Europe, Asia and Africa. Of specific interest were the Mediterranean islands of Rhodes and Cyprus and also Morocco.

Isolates were subjected to multilocus sequence typing and nucleotide polymorphism-based genome mapping. Sequence Type (ST) 411 affecting 17 patients was acquired in southern Europe, ST 1954 was identified in 15 patients who were infected in Africa and ST 343 infected 11 patients travelling to Thailand and Sri Lanka. This epidemiologic study demonstrates the power of molecular assay to identify both geographic location and where available vehicle of infection.

*Sira, L. et al Whole Genome Sequencing of Salmonella Chester Reveals Geographically Distinct Clusters, Norway 2000 - 2016 Euro Surveill 2019: 24: ES.2019.24.4.1800186